VAP Bundle Ventilator Associated Pneumonia Ventilator Associated Pneumonia ( VAP) is a lung infection that occurs in patients who are on mechanical ventilation for more than 48 hours. A VAP bundle is a set of Update on ventilator associated pneumonia F1000Research File:VAE, VAP and PNEU Definition Changes for 2015.webm Wikimedia Commons Preventive bundle approach decreases the incidence of ventilator associated pneumonia in newborn infants Journal of Perinatology Ventilator Associated Pneumonia (VAP) EMCrit Project