Can You Donate Plasma If You Smoke Weed? Get Facts Here! The Sanctuary We all know smoking and vaping isn't great for your health. But it doesn't stop you from being a blood or plasma donor. Just make sure to wait one hour after donating Cannabis Use and Blood Donation: Unmasking the Truth Can You Donate Blood If You Are A Smoker? Are vape pens, or e cigarettes, ever the better option? Ohio State Health & Discovery