Vape Juice Nicotine Levels for Dummies Did you know some vapes contain up to 50mg of nicotine? That's about the same as smoking 50 cigarettes. Nicotine is toxic and can lead to acute lung injury. Stay informed and Vaping Equivalents: How Many Puffs of Vape Equal One Cigarette? 1 electronic cigarette pod is roughly equal to 20 cigarettes' worth of nicotine, or 200 puffs. That's a lot! Make the choice not to let nicotine control your life. #EliminateTobacco and put Flavourless 50VG 50PG (30mL) by DV Labs