Non covalent interactions in the glutathione peroxidase active center and their influence on the enzyme activity Organic & Biomolecular Chemistry (RSC Publishing) Frontiers Research progress of glutathione peroxidase family (GPX) in redoxidation TJ. Glutathione peroxidase is an important enzyme in cellular antioxidant defense systems, detoxifying peroxides and hydroperoxides. As a component of the glutathione cycle, it protects the liver from reactive oxygen metabolites. Selenocysteine GPX1 (Glutathione Peroxidase, GSHPx) Gene Variants and Cardiovascular Revolution Health & Wellness Figure 3 from Glutathione Peroxidase 1 in Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities Semantic Scholar