Glutathione is such a critical soldier in our line of defense that our bodies make it themselves. We even have mechanisms that recycle and reuse it. But what happens when our toxic Bilirubin in clinical practice : Liver International Who's talking about this big problem? Low glutathione aa a causative big factor in gallstones. Why? Your biggest detoxification genes are the cytochrome P450 genes. These work very hard in eliminating most Glutathione deficiency and heart failure: a systematic review of human and animal evidence ScienceDirect Frontiers Glutathione: Pharmacological aspects and implications for clinical use in non alcoholic fatty liver disease