Benign Discoloration Poses Questions Melanosis Ilei Clinical Gastroenterology and Hepatology Pigmentation (melanosis) of the colon Stock Image C009 6107 Science Photo Library Melanosis coli Melanosis coli is dark brown black pigmentation of colorectal mucosa associated with chronic use of laxatives containing anthraquinone. Examples of such laxatives include senna and rhubarb derivatives. Clinical Importance: There is no association
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