B12 vitamin Store Intramuscular vs Subcutaneous Injections for vitamin B12 supplements. B12 Injection For Neuropathy CE Foot & Ankle Clinic, Nashville Lets do my first B12 injection together This is something Ive been nervous about for a long time, but today I finally did itand it honestly wasnt bad at all. I used the Union Medico needle guide Self injecting vitamin B12. Quick and painless jabs after a B12 by Dr Caroline Palmer Medium Vit B12 to resolve symptoms of burning, shooting pain, due to peripheral neuropathy, affecting the patients mobility . Typically patients have these symptoms due to diabetes, or autoimmune conditions