Collagen Supplements for Ehlers Danlos Syndrome and Hypermobility Understanding Ehlers Danlos Syndrome (EDS): Signs and Treatments : Alpenglow Pain & Wellness: Board Certified Interventional Pain Management Physicians The EhlersDanlos syndromes Nature Reviews Disease Primers Ehlers Danlos syndrome (EDS) is a group of 13 related genetic (heritable) connective tissue disorders. EDS, particularly the hypermobile type (hEDS), frequently overlaps with Postural Orthostatic Tachycardia Syndrome (POTS) and Mast Cell Activation Ehlers Danlos syndrome (EDS)