Role of glutathione in oxidative stress. During oxidative stress there Download Scientific Diagram Glutathione is the body's primary internal antioxidant, made using the amino acid cysteine, and it helps protect cells from oxidative stress. Beyond detoxification, research shows glutathione is involved in thyroid hormone metabolism, Glutathione, often dubbed the master antioxidant plays a crucial role in detoxification, immune function, and protecting our cells from oxidative stress. Here are some signs that your levels might be low: Persistent Glutathione: Antioxidant Properties Dedicated to Nanotechnologies The antioxidant glutathione ScienceDirect