Glutathione PDF) GlutathioneRelated Metabolite Levels and Enzyme Activities in Depression: A Systematic Review and MetaAnalysis A major breakthrough in brain science is shedding new light on the biology behind depression. Using advanced imaging, researchers have found that people with major depressive disorder have significantly lower levels of Depression, Genetics, and Mitochondrial Function Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation Scientific Reports