as someone who has an MTHFR gene mutation i have to supplement with methyl b12 via injection drip oral supplements my body doesnt make good use of it from Hydroxocobalamin vs. Methylcobalamin (B12) for MTHFR Methyl Life Supplements Causes of B12 deficiency and how its related to MTHFR? Bacteriostatic Water, Bac Water, UK. sterile solution.com Through gene testing I just got a little surprise i have a special mutation called MTHFR which reduces my ability to convert folate and B12 into active forms. So my friends @gameday_pasadena