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Metabolism: The carnitine shuttle and fatty acid metabolism (practice) Khan Academy Short Note On Carnitine Shuttle: Fatty acids are oxidized in mitochondria, and synthesized in the cytoplasm. Long chain fatty acids must form an active intermediate, fatty acyl CoA, before being oxidized inside mitochondria. Catherine Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non cell autonomous manner: Cell Reports Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health Disorders of Fatty Acid Metabolism Concise Medical Knowledge
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l-carnitine transports long chain fatty acids into mitochondria Carnitine in Mitochondrial Fatty Acid Transport and β-Oxidation

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