STUDENT CONSULT (ver. 2.3) Myth busting, Acetaminophen version. "Avoid Acetaminophen (Tylenol) because it causes glutathione depletion". Truth?? As a pediatrician and ER doctor and as moms we're often asked about this. And we understand why: Glutathione Transferase A1 an overview ScienceDirect Topics Role of Human Glutathione S Transferases in the Inactivation of Reactive Metabolites of Clozapine Chemical Research in Toxicology Did you know that high doses of paracetamol can be toxic to your liver? Paracetamol, also known as acetaminophen, is a commonly used painkiller that can have harmful effects on the body