Acetaminophen Toxicity: How Genetic Susceptibility Combines with Environmental Factors What is glutathione? Know as the most important antioxidant in the body, glutathione is an essential antioxidant manufactured in all cells, but primarily in the liver. It is essential because it Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression Nature Communications Changes in Glutathione Content in Liver Diseases: An Update Glutathione Metabolism an overview ScienceDirect Topics