Metabolism of acetaminophen (paracetamol) in plantstwo independent pathways result in the formation of a glutathione and a glucose conjugate Environmental Science and Pollution Research Springer Nature Link Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome Scientific Reports What is glutathione and why must we protect patient access to it? Figure 1: CMAJ Researchers are studying a possible link between acetaminophen (Tylenol) use during pregnancy and higher autism or ADHD risk. It may lower glutathione, an important antioxidant for brain development.