Are Nicotine Free Vapes Safe? Side Effects and Risks Velvet Cloud Get Involved Campaign for Tobacco Free Kids Don't be foolede cigs or vapes may be less harmful than cigarettes, but less harmful doesn't mean safe. Vapes can contain harmful substances including nicotine, heavy metals like lead, volatile organic compounds and Vaping without nicotine The advantages of nicotine free vapes Nonnicotine vapes may be marketed as safe, but many still contain chemicals, have unknown health effects, and aren't FDAregulated. Teens are using them more ofteneven alongside nicotine vapes. No ecigarette is risk free.