The Health Risks Of E Cigarettes Versus Traditional Cigarettes Henry Ford Health Detroit, MI Many people believe that vaping is less harmful than smoking, but that's a common misconception. In fact, in addition to nicotine, vapes can contain toxic chemicals that could be linked to cancer, Difference Between E Cigarette and Vape Difference Between E Cigarette vs Vape Vaping is on the rise. While e cigarettes don't contain tobacco, they may still contain many of the same toxic and cancer causing chemicals found in regular cigarettes. This includes: Acrolein (weed E Cigs & Oral Health: How Vaping Affects Gums & Teeth