The Electron Transport Chain and Pentose Phosphate Pathway biochemistry Glutathione at the Crossroads of Redox Homeostasis and Glucose Metabolism in Diabetes Mellitus Indian Journal of Clinical Biochemistry Springer Nature Link Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst 9. Oxidative Stress SimpleMed Learning Medicine, Simplified Glutathione (GSH) ZELLX